Item Type | Name |
Concept
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Protein-Tyrosine Kinases
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Concept
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Protein Binding
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Concept
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Protein Processing, Post-Translational
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Concept
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Protein-Arginine N-Methyltransferases
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Concept
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Protein Structure, Tertiary
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Concept
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Insulin-Like Growth Factor Binding Protein 5
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Concept
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BRCA1 Protein
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Concept
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Receptor Protein-Tyrosine Kinases
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Concept
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Insulin-Like Growth Factor Binding Protein 3
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Concept
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BRCA2 Protein
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Concept
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bcl-X Protein
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Concept
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Ribosomal Protein S6 Kinases, 90-kDa
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Concept
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Ubiquitin-Protein Ligases
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Concept
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MutS Homolog 2 Protein
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Concept
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Fanconi Anemia Complementation Group F Protein
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Concept
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Retinoblastoma Protein
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Concept
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Insulin-Like Growth Factor Binding Protein 2
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Concept
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Tumor Suppressor Protein p14ARF
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Concept
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Fanconi Anemia Complementation Group C Protein
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Concept
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AMP-Activated Protein Kinases
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Concept
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Protein Stability
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Concept
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Tumor Suppressor Protein p53
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Concept
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Protein Isoforms
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Concept
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Protein Kinase Inhibitors
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Concept
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Transcription Factor 7-Like 1 Protein
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Academic Article
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CDKN2 gene deletion is not found in chronic lymphoid leukaemias of B- and T-cell origin but is frequent in acute lymphoblastic leukaemia.
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Academic Article
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Preferential loss of expression of p16(INK4a) rather than p19(ARF) in breast cancer.
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Academic Article
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Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases.
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Academic Article
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Computerized analysis of mammographic parenchymal patterns for breast cancer risk assessment: feature selection.
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Academic Article
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Alterations of the 9p21 and 9q33 chromosomal bands in clinical bladder cancer specimens by fluorescence in situ hybridization.
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Academic Article
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Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations.
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Academic Article
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Prevalence of BRCA1 and BRCA2 mutations among clinic-based African American families with breast cancer.
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Academic Article
|
Gene-expression profiles in hereditary breast cancer.
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Academic Article
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Computerized analysis of digitized mammograms of BRCA1 and BRCA2 gene mutation carriers.
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Academic Article
|
Protein truncating BRCA1 and BRCA2 mutations in African women with pre-menopausal breast cancer.
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Academic Article
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EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer.
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Academic Article
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FANCF methylation contributes to chemoselectivity in ovarian cancer.
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Academic Article
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Computerized analysis of mammographic parenchymal patterns for assessing breast cancer risk: effect of ROI size and location.
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Academic Article
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Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
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Academic Article
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Computerized texture analysis of mammographic parenchymal patterns of digitized mammograms.
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Academic Article
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BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy.
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Academic Article
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Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment.
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Academic Article
|
Primary structure-based function characterization of BRCT domain replicates in BRCA1.
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Academic Article
|
AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.
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Academic Article
|
Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type.
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Academic Article
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Phase I trial of erlotinib-based multimodality therapy for inoperable stage III non-small cell lung cancer.
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Academic Article
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A compact VEGF signature associated with distant metastases and poor outcomes.
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Academic Article
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Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
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Academic Article
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Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers.
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Academic Article
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Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.
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Academic Article
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c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells.
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Academic Article
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Estrogen receptor alpha, BRCA1, and FANCF promoter methylation occur in distinct subsets of sporadic breast cancers.
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Academic Article
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RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers.
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Academic Article
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Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers.
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Academic Article
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Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.
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Academic Article
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Novel germline PALB2 truncating mutations in African American breast cancer patients.
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Academic Article
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Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes.
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Academic Article
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Clinical significance of KISS1 protein expression for brain invasion and metastasis.
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Academic Article
|
Risk of ipsilateral breast cancer in BRCA1 and BRCA2 mutation carriers.
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Academic Article
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High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients.
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Academic Article
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Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization.
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Academic Article
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RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.
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Academic Article
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Genetic variation in IGFBP2 and IGFBP5 is associated with breast cancer in populations of African descent.
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Academic Article
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CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
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Academic Article
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Searching for large genomic rearrangements of the BRCA1 gene in a Nigerian population.
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Academic Article
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Genetic susceptibility to breast cancer.
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Academic Article
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Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers.
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Academic Article
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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
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Academic Article
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Early onset HER2-positive breast cancer is associated with germline TP53 mutations.
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Academic Article
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ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing.
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Academic Article
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Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
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Academic Article
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MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion.
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Academic Article
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Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/ß-catenin signaling.
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Academic Article
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MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
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Academic Article
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A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer.
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Academic Article
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Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity.
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Academic Article
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Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers.
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Academic Article
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Inherited predisposition to breast cancer among African American women.
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Academic Article
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Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models.
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Academic Article
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Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
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Academic Article
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Expression of polycomb targets predicts breast cancer prognosis.
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Academic Article
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MYC overexpression and poor prognosis in sporadic breast cancer with BRCA1 deficiency.
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Academic Article
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DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.
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Academic Article
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An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.
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Academic Article
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Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mutation Carriers.
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Academic Article
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Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome.
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Academic Article
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BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
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Academic Article
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Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.
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Academic Article
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Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
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Academic Article
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Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.
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Academic Article
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Naturally occurring BRCA2 alternative mRNA splicing events in clinically relevant samples.
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Academic Article
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Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
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Academic Article
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Haplotype analyses of the c.1027C>T and c.2167_2168delAT recurrent truncating mutations in the breast cancer-predisposing gene PALB2.
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Academic Article
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Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
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Academic Article
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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
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Academic Article
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Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.
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Academic Article
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Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
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Academic Article
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Mutations in context: implications of BRCA testing in diverse populations.
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Academic Article
|
Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry.
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Academic Article
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Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
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Academic Article
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Clinical interpretation of pathogenic ATM and CHEK2 variants on multigene panel tests: navigating moderate risk.
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Academic Article
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Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.
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Academic Article
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Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers.
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Academic Article
|
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
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Academic Article
|
Cancer Susceptibility Genetic Testing in a High-Risk Cohort of Urban Ashkenazi Jewish Individuals.
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Academic Article
|
Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study.
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Academic Article
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Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers.
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Academic Article
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BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry.
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Academic Article
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The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries.
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Academic Article
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Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study.
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Academic Article
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USPSTF Recommendations for BRCA1 and BRCA2 Testing in the Context of a Transformative National Cancer Control Plan.
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Academic Article
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Two truncating variants in FANCC and breast cancer risk.
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Academic Article
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Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response.
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Academic Article
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Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.
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Academic Article
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Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer.
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Academic Article
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Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families.
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Academic Article
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Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon.
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Academic Article
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Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants.
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Academic Article
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p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.
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Academic Article
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A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.
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Academic Article
|
Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation.
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Academic Article
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Differences in somatic TP53 mutation type in breast tumors by race and receptor status.
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Academic Article
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Subtype-specific expression of MELK is partly due to copy number alterations in breast cancer.
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Concept
|
Enhancer of Zeste Homolog 2 Protein
|
Concept
|
MutL Protein Homolog 1
|
Concept
|
Protein Domains
|
Concept
|
Fanconi Anemia Complementation Group N Protein
|
Concept
|
MRE11 Homologue Protein
|
Concept
|
Ataxia Telangiectasia Mutated Proteins
|
Grant
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CHARACTERIZATION OF A TUMOR SUPPRESSOR GENE ON 9P
|
Academic Article
|
Mutational spectrum of breast cancer susceptibility genes among women ascertained in a cancer risk clinic in Northeast Brazil.
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Academic Article
|
Bilateral Oophorectomy and the Risk of Breast Cancer in BRCA1 Mutation Carriers: A Reappraisal.
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Academic Article
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Profile of Pathogenic Mutations and Evaluation of Germline Genetic Testing Criteria in Consecutive Breast Cancer Patients Treated at a North Indian Tertiary Care Center.
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Academic Article
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Tamoxifen and the risk of breast cancer in women with a BRCA1 or BRCA2 mutation.
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Academic Article
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The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
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Academic Article
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Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers.
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Academic Article
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Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation.
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